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I use slurry on synthetics too, especially when I am setting a bevel. I even go with slurry on a 600 grit sometimes when I have to work a big chip on a wedge or pre bevel set a wedge. I personally do...

Slurry helps with the cutting action of the stone.
For Japanese natural stones the slurry also breaks down to fined grit as you use it on the stone.