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If you don't care about particular size yes. One caveat though, if the original size is too large (I think over 2MB) it may not upload in the first place.

Some people are pretty picky and want...

I think if larger than 667x500 it will be resized down.

I don't think the smaller sizes are processed, most likely not, though someday I probably should set a filter to do a lossless compression...