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If the inclusive angle on a razor is in the 15 - 20 degree range then a bias towards one side will require only a very slight adjustment in the angle you hold your razor at to compensate. In reality...

I don't think it's possible for one side of the bevel to be sharper than the other. You can get different angles if the bevel is asymmetrical as with a kamisori grind - but, in my experience, that...