It depends on the exact nature of the grind and how hard the steel is. Some of the flexier full hollows dull quickly on my beard, but i've got other full hollows that are just a little stiffer that hold up just fine. Generally a quick stropping before I go against the grain does the trick, though even then the blades tend to need a refresh within 3-7 shaves.

The Henckels Friodurs are full hollow razors that are pretty highly recommended for tough beards.