Thread: Running kills my knees!

+1 on basil's and nun2sharp's advice. When I first began using a treadmill, my ankles hurt like the dickens. It was because my musculature was not toned. In short, I was out of shape. Try some warmup exercises before hitting the treadmill. Perhaps even some weight bags to drape over your ankles and perform some warmup exercises.

Keep in mind that cycling does not put as much stress on your joints as running. That is one reason why so many people opt for cycling over running.

You may also want to consider a fast walk on the treadmill at first, as opposed to running. After a month or two you can build up to a slow jog, then increase your speed from there.